Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

It was long believed that estrogens were good for women's health especially for heart and brain. A new study together with other current data challenge this dogma. Using data from a French population-based prospective study (the Three-City Study) including 5,644 postmenopausal women aged 65 years or older, the association of endogenous estradiol with the 4-year incidence of dementia was investigated. Based on 132 incident dementia cases, elevated estradiol level was identified as a predictor of dementia. Importantly, the risk associated with higher E2 levels was dramatically increased in women with diabetes compared with nondiabetic women. These findings have published in Neurology. Considering the expected increase in the number of elderly women with diabetes and dementia, more data on this topic are urgently needed.

© Esther 2019