Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

A meta-analysis recently confirmed the safety advantage of transdermal vs oral estrogens with respect to the risk of venous thromboembolism. However, the authors pooled all the studies, regardless of concomitant progestogens, and the heterogeneity reported in this meta-analysis was mainly due to the progestogens but not to the route of estrogen administration. This misinterpretation of the observational data led to discrepancies in rating the quality of evidence. See the Letter to the Editor of JCEM.

© Esther 2019