Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Hormones and Cardiovascular Disease
Director: Pierre-Yves Scarabin

 

Incidence of coronary heart disease (CHD) is lower in women than men of the same age. The gap between the two genders closes after the menopause, when CHD rates rise sharply and cardiovascular disease becomes the leading cause of death among women. It has been therefore hypothesized that women CHD advantage could be due to the protective effects of estrogens.

This potential cardioprotective effect has been challenged by new epidemiological data on endogenous sex hormones in relation to cardiovascular disease in the elderly. Analysis of the Three-City prospective cohort study published in the Journal of American Heart Association showed that there was an increased risk of ischemic arterial disease, including CHD and stroke, among postmenopausal women aged > 65 yrs with elevated plasma levels of estradiol.

 

 

© Esther 2019